ORGNTuesday, August 18, 2009

8:30 AM-11:50 AM Walter E. Washington Convention Center -- 207A, Oral
Small Molecule Therapeutic Agents
Organizer:Sanjay V. Malhotra
8:30 AMIntroductory Remarks
8:40 AMAntitumor compounds targeting the spliceosome by molecular concision of FR901464
Thomas Webb
9:05 AMBridging between HDAC inhibitors and therapeutic applications
Norikazu Nishino, Ryohei Furumai, Satoko Maeda, Nobuyuki Kobasi, Akihiro Ito, Junichi Nakagawa, Minoru Yoshida
9:30 AMCellular delivery of therapeutics using the bacterial protein toxin subunit Shiga-B
Jean-Claude Florent
9:55 AMDesign and synthesis of indenoisoquinoline topoisomerase I inhibitors
Mark Cushman, Xiangshu Xiao, Alexandra Ioanoviciu, Andrew Morrell, Muthukaman Nagarajan, Yunlong Song, Zhi-Yu Shao, Evgeny Kiselev, Maris A. Cinelli, Bart Staker, Alex B. Burgin, Lance Stewart, Smitha Antony, Glenda Kohlhagen, Thomas S. Dexheimer, Yves Pommier
10:20 AMIntermission
10:35 AMDesign of small molecule drugs targeting quadruplex nucleic acids
Stephen Neidle
11:00 AMDesign of small molecule inhibitors of human voltage gated sodium channels for treatment of prostate cancer
Gary Davis, Thomas Walls, Simeng Suy, Li Zhang, Milton L. Brown, Sivanesan Dakshanamurthy
11:25 AMPerturbing the cell death pathway for therapeutic benefit in cancer: Sounds like a good idea but does it work?
Mark Lawler

Small Molecule Therapeutic Agents -- Next Session

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 238th ACS National Meeting, Washington, DC, August 16-20, 2009