Ionic liquid-supported (ILS) (S)-pyrrolidine sulfonamide, an effective organocatalyst for the enantioselective Michael addition to nitroolefins

ORGN 721

Bukuo Ni, bukuo_ni@tamu-commerce.edu, Qianying Zhang, Kritanjali Dhungana, and Allan D. Healdey. Department of Chemistry, Texas A&M University-Commerce, Commerce, TX TX 75429-301
A new class of ionic liquid supported (ILS) (S)-pyrrolidine sulfonamide organocatalyst has been developed and shown to be very an effective catalyst for the asymmetric Michael addition reactions of ketones and aldehyde to nitroolefins with moderate to high enantio- and diastereoselectivities. This ILS organocatalyst is also easily recycled and could be reused for at least five times without significant loss of its ability to affect the outcome of the asymmetric reactions.

 

Heterocycles and Aromatics, Asymmetric Reactions and Syntheses and Total Synthesis of Complex Molecules
7:00 PM-9:00 PM, Wednesday, August 19, 2009 Walter E. Washington Convention Center -- Ballroom C, Poster

Division of Organic Chemistry

The 238th ACS National Meeting, Washington, DC, August 16-20, 2009