ORGN 219 |
| A variety of methods for the direct amination of alkenes will be discussed. Palladium-catalyzed hydroamination, haloamination, arylamination and diamination reactions are powerful tools for the stereoselective synthesis of nitrogen heterocycles. All these reactions stem from differential functionalization of a common palladium-alkyl intermediate by the appropriate introduction of various external reagents. Acid-catalyzed oxidative amination reactions have proven to be a useful alternative route to diamine and aminoalcohol products. The mechanisms of these transformations will also be discussed, especially regarding the potential scope and utility of Pd(II)-Pd(IV) catalytic cycles in oxidative chemistry.
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Young Academic Investigators
8:00 AM-12:00 PM, Monday, August 17, 2009 Walter E. Washington Convention Center -- 207A, Oral
Division of Organic Chemistry |
