ORGN 695 |
| Host-guest chemistry involves the complimentary binding between two molecules and can serve as the basis for analytical detection and signaling, as well as a model for receptor-ligand binding in biological systems. Host molecules have been synthesized to selectively bind proteins and enzymes, and have been used as optical sensors, electrochemical sensors, and supramolecular catalysts. Cyclotriveratrylene (CTV), a common supramolecular scaffold, has been extensively employed in guest-host chemistry. CTV-oxime derivatives in crown and saddle conformations with a thiotic acid sulfur linkage have been synthesized for direct patterning on a gold surface via Dip-Pen Nanolithography (DPN). Tapping mode atomic force microscopy (TMAFM) data provided evidence for the ability to directly write supramolecular SAMs on a surface with evidence obtained for binding of guests at the surface.
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Heterocycles and Aromatics, Asymmetric Reactions and Syntheses and Total Synthesis of Complex Molecules
7:00 PM-9:00 PM, Wednesday, August 19, 2009 Walter E. Washington Convention Center -- Ballroom C, Poster
Division of Organic Chemistry |
