Synthesis of phthalimido β-lactams via the Staudinger reaction using polyaromatic imines

ORGN 650

Debasish Bandyopadhyay, bandyopad@utpa.edu1, Monica Xavier, banik@utpa.edu1, and Bimal K. Banik, banik@panam.edu2. (1) Department of Chemistry, University of Texas-Pan American, 1201 W. University Drive, Edinburg, TX 78539, (2) Department of Chemistry, The University of Texas-Pan American, 1201 West University Drive, Edinburg, TX 78541
Synthesis of a few trans 3-phthalimido substituted -lactams from polyaromatic imines has been achieved following Staudinger reaction. The formation of the trans -lactams has been explained through an isomerization of the intermediate iminium ion.