ORGN 789 |
| Phenanthridines have attracted considerable attention in medicinal chemistry and in material science due to their biological activity and their presence in a variety of significant natural products and synthetic dye-stuffs. recently we have developed simple and convenient one-pot procedure, TFA-mediated reaction of 2-arylanilines with arylaldehydes to afford 6-substituted phenanthridines. The operational simplicity of this process and use of simple reactants without requirement of synthesis of complicated precursors, strictly anhydrous conditions, air-sensitive organometallic reagents, or expensive metal catalysts make it particularly attractive for library construction. |
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Heterocycles and Aromatics, Asymmetric Reactions and Syntheses and Total Synthesis of Complex Molecules
7:00 PM-9:00 PM, Wednesday, August 19, 2009 Walter E. Washington Convention Center -- Ballroom C, Poster
Division of Organic Chemistry |