ORGN 768 |
The benzannulated enediynyl alcohol 3 was synthesized from condensation between indanone 2 and the lithium acetylide derived from 1. The transformation from 3 to 5 involved a reduction followed by a cascade sequence of cyclization reactions. Treatment of 5 with Me3SiI followed by an intramolecular alkylation reaction then provided 7 containing a partially hydrogenated cyclopentaphenanthrene substructure. |
Heterocycles and Aromatics, Asymmetric Reactions and Syntheses and Total Synthesis of Complex Molecules
7:00 PM-9:00 PM, Wednesday, August 19, 2009 Walter E. Washington Convention Center -- Ballroom C, Poster
Division of Organic Chemistry |