PHYSThursday, August 21, 2008

8:00 AM-11:40 AM Loews -- Commonwealth D, Oral
Protein Folding Dynamics: Experiment and Theory
Organizers:Feng Gai
Angel E. Garcia
Presiding:Kevin W. Plaxco
8:00 AMInsertion, folding and assembly of integral membrane helical structures
Charles L. Brooks III, Lintao Bu
8:40 AMLong timescale and multitrajectory molecular dynamics simulations of the penetration of indolicidin into lipid bilayer: A comprehensive mechanism
Chin-Wei Tsai, Ning-Yi Hsu, Yung Chang, Hui-Hsu Gavin Tsai, Ruoh-Chyu Ruaan
9:00 AMMembrane protein folding: Effects of tryptophan microenvironment and soluble domain on the thermodynamics and structure of an integral membrane protein
Judy E. Kim, Katheryn M. Sanchez, Tiffany J. Neary
9:20 AMMolecular design of TM helical bundle as a tool for probing the feature that drives folding in membrane
Yao Zhang, Daniel W. Kulp, James D. Lear, William F. DeGrado
9:40 AMUltraviolet resonance Raman spectroscopy of a membrane-bound beta-sheet peptide as a model for membrane protein folding
Hannah S. Shafaat, Katheryn M. Sanchez, Tiffany J. Neary, Judy E. Kim
10:00 AMIntermission
10:20 AMMembrane-mediated folding of alpha-synuclein
Elizabeth Middleton, Adam Trexler, David Eliezer, Elizabeth Rhoades
11:00 AMBinding of α-synuclein to membrane mimics and calcium ions
Bert T. Lai, Jennifer C. Lee, Jay R. Winkler, Harry B. Gray
11:20 AMLinking enzyme conformational dynamics to catalytic function with single-molecule FRET
Yan-Wen Tan, Jeffery A. Hanson, Karl Duderstadt, Sucharita Bhattacharyya, Jason Brokaw, Jhih-Wei Chu, Haw Yang

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The 236th ACS National Meeting, Philadelphia, PA, August 17-21, 2008