COMPSunday, August 17, 2008

8:00 AM-12:10 PM Sofitel -- Versailles, Oral
Pharmacology: The Forgotten Art of Drug Discovery
Organizer:Tudor I. Oprea
8:00 AMEstrogen receptors as therapeutic targets in breast cancer
Eric A. Ariazi, V. Craig Jordan
8:30 AMLocalization, distribution, and pharmacology of G protein-coupled estrogen receptor GPR30
Eugen Brailoiu, G. Cristina Brailoiu, Siok Le Dun, Elena Deliu, Eric A. Ariazi, Jeffrey B Arterburn, Eric R. Prossnitz, Tudor I. Oprea, V. Craig Jordan, Nae J. Dun
9:00 AMOpioid agonist-selective signaling.
Ping Y. Law
9:30 AMHTS and pharmacology of multiplexed small GTPase targets by flow cytometry
Larry A Sklar, Zurab Surviladze, Gary M. Bokoch, Cristian G. Bologa, Bruce Edwards, Tudor I. Oprea, Oleg Ursu, Anna Waller, Hui Zhang, Angela Wandinger-Ness
10:00 AMIntermission
10:10 AMMechanisms of allostery and membrane attachment in Ras GTPases
Alemayehu A. Gorfe, Barry J. Grant, J Andrew McCammon
10:40 AMVirtual screening provides a mechanism for finding a chemical tool from a biological messenger
Grant Churchill
11:10 AMPerspectives and learnings on in silico pharmacology and biological fingerprints
Jonathan S. Mason
11:40 AMUsing a network pharmacology approach to better understand adverse drug reactions
Josef Scheiber, Jeremy L. Jenkins, Dmitri Mikhailov, Sai Chetan K. Sukuru, Steven Whitebread, Jacques Hamon, Laszlo Urban, Kamal Azzaoui, Meir Glick, John W. Davies

Pharmacology: The Forgotten Art of Drug Discovery -- Next Session

Symposium Grid -- Division of Computers in Chemistry -- Session Listing

Symposium Grid -- Chemistry for Health -- Session Listing

Symposium Grid -- Drug Discovery -- Session Listing

The 236th ACS National Meeting, Philadelphia, PA, August 17-21, 2008