Effect of subphase glycerol on lipid monolayers

PHYS 314

Kseniya Gavrilov, gavrilov@uchicago.edu, Department of Chemistry, University of Chicago, 929 E. 57th St., CIS-ESB31, Chicago, IL 60637, Luka Pocivavsek, lukap@uchicago.edu, Department of Chemistry, The Institute for Biophysical Dynamics and The James Franck Institute, University of Chicago, 929 E. 57th St., CIS-ESB31, Chicago, IL 60637, and Ka Y. C. Lee, Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637.
Lipid monolayers at an air-water interface can be modeled as thin elastic membranes floating on a fluid subphase. Under compression these membranes deviate from their flat geometry and enter the third dimension, a process called collapse. Traditionally, models of collapse have concentrated on monolayer elastic properties independent of subphase effects. Here we focus on subphase effects on monolayer collapse by examining lipid monolayers atop subphases composed of water/glycerol mixtures. Water and glycerol are relatively similar in their density, dielectric constant, and surface tension, but differ in their viscosity by three orders of magnitude. This system allows us to explore the role of subphase viscosity on monolayer collapse, as well as complex glycerol-lipid interactions.
 

PHYS Poster Session - Water Mediated Interactions
7:30 PM-10:00 PM, Wednesday, August 20, 2008 Pennsylvania Convention Center -- Hall C, Poster

Division of Physical Chemistry

The 236th ACS National Meeting, Philadelphia, PA, August 17-21, 2008