| MEDI | Wednesday, April 9, 2008 | ||
9:00 AM-12:20 PM Morial Convention Center -- La Nouvelle, Blrm. A, Oral | |||
The Hit to Lead Process: Identifying the Most Promising Chemotypes in the Fewest Possible Steps | |||
| Sponsored by: | MEDI | ||
| Financially supported by: | Sigma-Aldrich Corporation | ||
| Organizers: | Shelli R. McAlpine Samuel W. Gerritz | ||
| 9:00 AM | 184 | Multiple parallel approaches to steroid hormone receptor lead identification David G. Jones, Peter J. Brown, Margaret Clackers, David Gray, Melissa Gomez, William J. Hoekstra, Istvan W. Kaldor, Lara Kallander, Millard H. Lambert, Hu Li, Xi Liang, Kevin Madauss, Aaron B. Miller, Robert A. Noe, Rosemary Sasse, Eugene L. Stewart, L. William Stuart, Scott K. Thompson, Philip Turnbull, Manon Villeneuve, David Washburn, Shawn Williams, Timothy M. Willson | |
| 9:40 AM | 185 | A novel inhibitor of thyroid hormone receptor function R. Kiplin Guy | |
| 10:20 AM | 186 | Discovery and optimization of acyl guanidines as novel BACE-1 inhibitors Samuel W. Gerritz, Shuhao Shi, Weixu Zhai, Shirong Zhu, Lorin A. Thompson, Jeremy H. Toyn, Jere E. Meredith, Andrew C. Good, Jodi K. Muckelbauer, Daniel M. Camac, Dharmpal S. Dodd, Lynda S. Cook, Ramesh Padmanabha, Charles F. Albright, Michael J. Sofia, Michael A. Poss, John E. Macor | |
| 11:00 AM | 187 | Discovery and development of allosteric modulators of Class A and Class C GPCRs Craig W Lindsley | |
| 11:40 AM | 188 | Hsp90 inhibitors: The journey from a designed lead to a clinical candidate Gabriela Chiosis | |
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008