| MEDI | Sunday, April 6, 2008 | ||
1:30 PM-4:50 PM Morial Convention Center -- La Nouvelle, Blrm. A/B, Oral | |||
First Time Disclosure of Clinical Candidates | |||
| Sponsored by: | MEDI | ||
| Financially supported by: | Wyeth | ||
| Organizer: | Andrew Stamford | ||
| 1:30 PM | 18 | Discovery of MK-7009: A novel macrocyclic HCV NS3/4A protease inhibitor John A. McCauley, Michael T. Rudd, Charles J. McIntyre, Kevin T. Nguyen, Joseph J. Romano, John W. Butcher, M. Katharine Holloway, Bang-Lin Wan, Steven S. Carroll, Jillian M. DiMuzio, Donald J. Graham, Steven W. Ludmerer, Shi-Shan Mao, Mark Stahlhut, Christine Fandozzi, Nicole Trainor, David B. Olsen, Joseph P. Vacca, Nigel J. Liverton | |
| 2:10 PM | 19 | Design, synthesis and biological profile of BMS-641988: A novel AR antagonist for the treatment of advanced prostate cancer Mark Salvati, Aaron Balog, Rampulla Richard, Soren Giese, Steven H. Spergel, Andrew J. Nation, Raj N. Misra, Kenneth Leavitt, Soong-Hoon Kim, Hai-Yun Xiao, Weifeng Shan, Greg Vite, Ricardo Attar, Marco Gottardis, Janet Dell Dell, Maria Jure-Kunkel, Jieping Geng, Cheryl Rizzo, Mary Obermeier, Stanley R. Krystek Jr., Foster William, Thomas Spires Jr., Carrie Xu, Arvind Mathur, Robert Jeyaseelan, Dan Kukral, Stephanie Powlin, Xue-Qing Chen | |
| 2:50 PM | 20 | Discovery of APD791: A potent and selective 5HT2A inverse-agonist for the treatment of cardiovascular disorders Bradley R. Teegarden, Yifeng Xiong, Sonja Strah-Pleynet, Peter I. Dosa, Honnappa Jayakumar, Jin Sun Choi, Marc Decaire, Martin Casper, Lan Pham, Konrad Feichtinger, Brett Ullman, Katie Elwell, John Adams, Juan Ramirez, William Thomsen, Diane Yuskin, Michael Morgan, Abu Sadeque, Weichao Chen, Paul Maffuid, Hussien Al-Shamma, Graeme Semple, Robert R. Webb, Daniel Connolly | |
| 3:30 PM | 21 | Discovery of a second generation FBPase inhibitor, MB07803, with reduced metabolism and improved oral bioavailability Qun Dang, Paul D. van Poelje, Robert H Lemus, Feng Tian, Haiqing Li, Scott C Potter, James Fujitaki, David Linemeyer, Mark D. Erion | |
| 4:10 PM | 22 | From virtual screening to clinic: Discovery of Cevoglitazar T. R. Vedananda, Mike Sabio, James Stanton, Hollis Tomaselli, James Fraser, Goli Naderi, Jenny Tan, Travis Stams, Brian Boettcher, Barbara Fanelli, Jianping Gao, Richard Deacon, Shari Caplan, Ping Chen, Beatriz Dardik, Ricardo Chatelain | |
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008