INOR 378 |
| This award address will present a brief retrospective look at my career in coordination chemistry. The link between Nature's metal ion selectivity in metal complexation (siderophores) and the design of metal-ion selective agents for applications as diverse as magnetic resonance imaging and metal detoxification will be outlined. This will be followed by the central focus of this presentation: nanometer scale, chiral, molecular flasks formed using labile, metal-ligand interactions. These clusters are highly negatively charged and very water-soluble. However they have hydrophobic interiors that strongly and selectively encapsulate hydrophobic cationic guests. Because of trigonal propeller chirality at the metal vertices and mechanical linkage between the metal vertices, these clusters are homochiral and resolvable. Enzyme-like catalysis of 3 to 4 orders of magnitude rate enhancement has been seen. Recent results and guesses about the future will be presented. |
|
ACS Awards to Inorganic Chemists
8:10 AM-12:50 PM, Monday, April 7, 2008 Morial Convention Center -- La Louisiane, Blrm. C, Oral
Division of Inorganic Chemistry |