On bioseparations and gas antisolvent precipitation in the isolation of sclareol

I&EC 66

Xenia Tombokan1, Remil Aguda1, David Danehower, david_danehower@ncsu.edu2, Ruben G Carbonell, ruben@ncsu.edu1, and Peter K Kilpatrick, peter_kilpatrick@ncsu.edu1. (1) Department of Chemical and Biomolecular Engineering, North Carolina State University, EB1, 911 Partners Way, Raleigh, NC 27695-7905, (2) Department of Crop Science, North Carolina State University, 4324A Williams Hall, Raleigh, NC 27695
Over the past 24 years, Ruben Carbonell and I have collaborated on 30 papers and 8 patents, mostly associated with protein purification and the interaction of proteins and macromolecules with surfaces. The theme throughout the majority of this work was creating new molecules and molecular assemblies with surface-active properties, affinity for binding proteins, and colloidal dimensions. In this retrospective, I will review some of the highlights of that research, with a particular emphasis on the collection of insights that came together with each innovation. I will conclude with a vignette focused on the latest research collaboration in which we have used the novel thermodynamic properties of carbon dioxide swollen organic solvents to separate nutraceuticals from plant materials.
 

Industrial and Engineering Chemistry Divisional Fellow Award Symposium - Dr. Ruben Carbonell
1:30 PM-4:25 PM, Tuesday, April 8, 2008 Morial Convention Center -- Rm. 231, Oral

Division of Industrial & Engineering Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008