SOCED 7 |
| Degradable polymers based on polyanhydrides are essentially polymeric prodrugs; the polymers hydrolytically degrade into salicylic acid, just as aspirin hydrolyzes into salicylic acid upon ingestion. This talk describes medical applications where the polymer serves as a temporary barrier that degrades into therapeutically active molecules such as non-steroidal anti-inflammatory drugs (NSAIDs) and concurrently releases admixed antimicrobials. We build upon our progress with salicylate-based polymers to create new NSAID-based polymers (PolyNSAIDs) that simultaneously reduce inflammation, control pain, and eliminate bacteria to not only address periodontal indications, but also deep bone infections, restenosis, and other related inflammatory diseases. More recently, we've expanded our program to include PolyAntibiotics and PolyAntiseptics useful for simultaneously controlling pain, inflammation and infection. |
|
Polymers in Sports
1:00 PM-2:00 PM, Sunday, April 6, 2008 Hilton New Orleans Riverside -- Grand Blrm C, Oral
Society Committee on Education |