FUEL 183 |
| Carbon monoxide dehydrogenases (CODHs)are structurally resolved metalloproteins functioning in aerobic and anaerobic chemolithoautotrophic bacteria and archaea. They catalyze the oxidation of the highly toxic poison gas CO to CO2 and play an important role in climate related cycles of atmospheric gases. Two main classes of CODHs can be distinguished. The heterohexameric enzymes from aerobic bacteria and the homodimeric enzymes from anaerobic bacteria or archaea. The former contain a unique [CuSMoO2] cluster in their active site, whereas the latter employ a unique [Ni-4Fe-5S] cluster. Studies employing compounds structurally related to CO have generated information on the interaction of CO at these metal active sites and how the reaction product CO2 is being formed. These clusters are subject to posttranslational maturation which is another topic to be discussed. |
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Hybrid Nanotechnologies for an Enhanced CO2 Fixation
8:50 AM-11:45 AM, Wednesday, April 9, 2008 Morial Convention Center -- Rm. 240/241, Oral
Division of Fuel Chemistry |