Reaction resonance is a frontier topic in chemical dynamics research, and it is also essential to the understanding of mechanisms of elementary chemical reactions.  In this presentation, we will describe a recent combined experimental and theoretical study on the benchmark F+H₂ reaction.  Experimental evidence of reaction resonances has been detected in a full quantum state resolved reactive scattering study of the F+H₂ reaction.  Highly accurate full quantum scattering theoretical modeling shows that the reaction resonance is caused by two reaction resonance states.  Further studies show that quantum interference is present between the two reaction resonance states for the forward scattering product.  This study is a significant step forward in our understanding of chemical reaction resonances in the benchmark F+H₂ system. Further experimental studies on the effect of H₂ rotational excitation on dynamical resonances were carried out.  Dynamical resonances on the F+H₂(j=1) reaction have also been observed.  A more recent study on the F+HD system has also been carried out.  The isotope substitution actually provides an extremely sensitive probe to the reaction resonance potential surface in this important system.