Detection of volatile and semivolatile target odor compounds associated with drugs, explosives, and residual solvents in pharmaceuticals by ion mobility spectrometer

CHED 225

Yisenny Delgado, ydelg001@fiu.edu1, Monica Joshi2, Hanh Lai2, Patty Guerra2, and José R. Almirall, almirall@fiu.edu2. (1) Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, (2) Department of Chemistry and Biochemistry and International Forensic Research Institute, Florida International University, 11200 SW 8th Street, CP 194, miami, FL 33199
The detection of very low levels of explosives and drugs is of interest to law enforcement and homeland security and the detection of industrial solvents is of interest to the pharmaceutical industry. This presentation describes the detection and quantitative analysis of target odor compounds using a pre-concentration (Solid Phase Microextraction) technique coupled to a field detection instrument (Ion Mobility Spectrometer). SPME-GC-MS will be used as a reference and quantitative analysis tool to compare to the SPME-IMS results. Detection and quantification limits will be determined for various target odor compounds that are characteristic for the presence of some drugs, explosives, and residual solvents in pharmaceutical products. Some examples of the target compounds described in this paper include the detection of Methyl Benzoate for the presence of Cocaine, β- Caryophyllene for the presence of Cannabis and Diphenyl Amine (DPA) and Ethyl Centralite (EC) for the presence of smokeless powders.
 

Undergraduate Research Poster Session: Analytical Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008