Synthesis of phenoxide ligands and titanium catalyzed hydroaminations

CHED 495

Kenneth Awasung, kawasung@bridgew.edu and Stephen A. Waratuke, swaratuke@bridgew.edu. Department of Chemistry, Bridgewater State College, Conant Science Building 316, Bridgewater, MA 02325
The synthesis and study of bulky phenoxides with alkyl and aromatic amine groups are of interest in our group. We have been evaluating ways to incorporate nitrogen functionalities into bulky phenols based upon the success of known phenoxides, salens, and aromatic amines to serve as early transition metal catalysts. My work on the synthesis of a group of bulky phenols using simple aldol condensation and michael addition chemistry will be the presented. The synthetic work involves the techniques of refluxing, extraction, purification, and characterization tools. I have also begun to study the use of titanium based catalysts to perform hydroamination reactions and intra-molecular hydroaminations. This has been an ongoing interest within our research group and remains a promising area of research. I will report upon our progress towards developing the usage of titanium aryl oxides comprised of known phenols and our new phenoxide analogs for use as hydroamination catalysts.