CHED 384 |
| Ionic liquids are molten salts and are considered “green” solvent because unlike the typical volatile organic solvents they replace, ionic liquids have no measurable vapor pressure, remain in the liquid state throughout a temperature range of 200oC – 300oC and are easily recycled. Ionic liquids are usually composed of a large organic cation and a smaller inorganic anion and can be customized, like organic solvents, to dissolve a wide range of organic molecules including biological molecules. Hundreds of new ionic liquids are being synthesized yearly and very little research exists on the long-term effects of ionic liquids on biological systems. We characterized the extent of damage to calf thymus DNA solubilized in 5% 3-methyl-1-butylimidazolium chloride after exposure to varying concentrations of hydrogen peroxide. Our initial results show less DNA damage from hydrogen peroxide to the calf thymus DNA solubilized in 5% 3-methyl-1-butylimidazolium chloride as compared to the DNA solubilized in 0.10 M sodium phosphate buffer. Acknowledgements: This research is supported by the Department of Defense through the U.S. Army Engineer Research and Development Center in Vicksburg, MS; Contract #W912HZ-06. |
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Undergraduate Research Poster Session: Chemical Education
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster
Division of Chemical Education |