Synthesis of PAMAM dendrimers to be functionalized as drug delivery agents: Comparing product quality to commercially available sources

CHED 345

Katherine Byrd, Sesily Macon, Danielle Matthews, and Stassi C DiMaggio, scdimagg@xula.edu. Department of Chemistry, Xavier University of Louisiana, 1 Drexel Dr, New Orleans, LA 70125
Dendrimers, synthetic organic star-branched polymers, have recently been successfully conjugated to various small molecules to create multifunctional nanotherapeutics, specifically drug delivery systems. Currently, various poly(amidoamine) dendrimer generations are being synthesized and their quality compared to that of commercially available dendrimers. The cost effectiveness of synthesizing dendrimers in-house combined with the level of product quality will be evaluated. Upon successful completion, these dendrimers will be functionalized to create nanotherapeutics used in drug delivery.
 

Undergraduate Research Poster Session: Nanotechnology
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008