Synthetic studies of spiroketal enol ether natural products

CHED 503

Elizabeth N. Lakin, elakin@bates.edu and Jennifer L. Koviach-Côté. Department of Chemistry, Bates College, 5 Andrews Rd, Lewiston, ME 04240
Spiroketal enol ethers are common motifs among natural products isolated from plants in the Asteraceae family. This project describes our attempts to form spiroketal enol ethers by addition of an internal acetal to an activated pendant alkyne.