Progress toward the synthesis of dragmacidin alkaloids

CHED 421

Darryl R. Miles, darryl_r_miles@georgiasouthern.edu and Christine R. Whitlock, cwhitlock@georgiasouthern.edu. Department of Chemistry, Georgia Southern University, P.O. Box 8064, Statesboro, GA 30460-8064
Progress towards the synthesis of novel derivatives of the biologically active dragmacidin alkaloids will be presented. Utilizing a three-step procedure, N-substituted 3,6-bisindolylpiperazine-2,5-diones have been synthesized from sarcosine anhydride. These products are being prepared for submission to the Cancer Research Institute for comparative studies.
 

Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008