CHED 487 |
| Azulene undergoes electrophilic aromatic substitution primarily at the 1 and 3 positions. Reaction with perfluorinated acid anhydrides and trichloroacetic anhydride occurs at room temperature without a Lewis acid catalyst. Consequently, we have adapted a literature procedure [Mathias, L. J.; Overberger, C. G. J. Org. Chem. 1980, 45, 1701] to synthesize several 1-substituted and 1,3-disubstituted azulenic ketones of the type 1 and 2.
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Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster
Division of Chemical Education |
