Determination of mutational changes through molecular genotyping

CHED 814

Nicole L. Klein, Seton Hill University, 1 Seton Hill Drive, Greensburg, PA 15601 and John A. Cramer, Department of Chemistry, Seton Hill University, 1 Seton Hill Drive, Greensburg, PA 15601.
Through the use of methods such as microdissection, PCR amplification, sequencing, and a patented test called PathFinderTG, cancer-related mutations can be determined, providing an early and definitive diagnosis for both doctor and patient. Tests measure the loss of heterozygosity present, which quantifies the extent of the mutational change. RedPath Integrated Pathology's technology is used in difficult oncology cases, integrating traditional pathology with genomics.
 

Undergraduate Research Poster Session: Biochemistry
2:00 PM-4:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008