Synthesis and biological activity of thymol derivatives

CHED 459

Michael Haltom, mh148712@reddies.hsu.edu, Rebecca Staton, rs152954@reddies.hsu.edu, and Jay P Deville, devillej@hsu.edu. Department of Chemistry, Henderson State University, 1100 Henderson Street, Arkadelphia, AR 71999-0001
Results on synthetic efforts directed toward thymol derivatives and subsequent biological testing will be presented. Derivatives of the monoterpene antibiotic thymol were prepared using standard reactions of organic chemistry. These derivatives were tested for bioactivity using the Bauer-Kirby disk susceptibility test. Comparing diameters of inhibition zones resultant from thymol to those resulting from the thymol derivatives allowed the pharmacophore of thymol to be probed.
 

Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008