Loading and release characteristics of halloysite

CHED 323

John Christopher Wuellner, C08John.Wuellner@usafa.edu1, Margaret H. Rakowsky, margaret.rakowsky@usafa.edu1, Barry W. Hicks1, and Glenn R. Johnson2. (1) Department of Chemistry, US Air Force Academy, 2355 Fairchild Dr, Suite 2N225, USAF Academy, CO 80840, (2) Microbilogy and Applied Biochemistry, Airbase Technologies Division, Air Force Research Laboratory, U. S. Air Force, Tyndall Air Force Base, FL 32403
Halloysite is an aluminum silicate material that forms nanotubes. This material has many possible applications in controlled release of molecules. The Air Force is interested in loading halloysite with proteins such as lysozyme to provide for further protection from biological warfare agents. Proteins may interact with the surface of halloysites through hydrophobic or electrostatic interactions and be released slowly. In this work we are utilizing fluorescent probes including mutant fluorescent proteins to investigate the loading and release characteristics of halloysite.