Synthetic studies on (+)-boronolide

CHED 504

Kevin J. Quinn, kquinn@holycross.edu, John M. Curto, jmcurt08@holycross.edu, and Truong Vo, tvo08@holycross.edu. Department of Chemistry, College of the Holy Cross, One College Street, Worcester, MA 01610
An approach to an asymmetric total synthesis of (+)-boronolide is described. Central to the efficiency of the synthesis is the implemenation of a tandem ring-closing/cross metathesis/alkene isomerization in which both dihydropyranone formation and side-chain extension are accomplished. Studies on this transformation as well as efforts aimed at completion of the synthesis will be presented.
 

Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008