Iron(III) chloride mediates inter-Qbeta bacteriophage interactions

ENVR 269

Nathan W. Schmidt1, Steve Barr2, Erik Luijten2, and Gerard C. L. Wong2. (1) Department of Physics, University of Illinois, 1110 West Green St., Urbana, IL 61801, (2) Department of Materials Science and Engineering, University of Illinois, 1304 West Green St., Urbana, IL 61801
Iron(III) chloride is used as a coagulation agent in sewage treatment and drinking water production to remove water-borne pathogens and other contaminants. Although it is commonly used, the flocculation abilities of iron(III) chloride is not understood at a fundamental physics level. Understanding the underlying microphysical processes of coagulants can assist in the design of novel materials with specific activity toward emerging pathogens. To better understand the effect of iron(III) chloride on aqueous contaminants, we use the Qbeta bacteriophage as a surrogate water-borne pathogen. Small angle X-ray scattering is used to characterize the inter-Qbeta interaction between viruses over a range of trivalent iron salt concentrations. We use a novel method to extract directly from scattering data the second virial coefficient of this process, which indicates the onset of attraction. We present preliminary results of this study, which will be compared to molecular dynamic simulations.