Antibody-polymer bead conjugation determination via surface Plasmon resonance and quartz crystal microbalance

POLY 114

Will Gray, will.gray@usm.edu1, Bing Yuan, Bing.Yuan@usm.edu1, Gordon C. Cannon, gordon.cannon@usm.edu2, Sabine Heinhorst2, and Sarah E. Morgan, sarah.morgan@usm.edu1. (1) School of Polymers and High Performance Materials, The University of Southern Mississippi, 118 College Dr., #10076, Hattiesburg, MS 39406, (2) Department of Chemistry and Biochemistry, The University of Southern Mississippi, S.S. Box 5043, Hattiesburg, MS 39406
Antibody-antigen interactions are the basis for laboratory assays providing identification and quantification of specific antigens. They are widely accepted in detection devices of bacteria and viruses due to their specificity and accuracy. New methods of designing and producing antibodies based on recombinant DNA techniques have opened even greater possibilities for integrating these molecules into biosensor platforms. In the current study, the antigen binding behavior of antibodies conjugated to polymer beads is evaluated utilizing surface Plasmon resonance (SPR) and quartz crystal microbalance (QCM) techniques.
 

Undergraduate Research in Polymer Science
6:00 PM-8:00 PM, Sunday, April 6, 2008 Morial Convention Center -- Hall A, Poster

Division of Polymer Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008