Design of polyester-based biomaterials: A structure-property approach

POLY 270

Valerie V. Sheares, ashby@email.unc.edu1, Andrew H. Brown, ahbrown@unc.edu1, Benjamin F. Pierce, bfpierce@email.unc.edu1, Jinrong Liu, ljramy@email.unc.edu2, and Peter Uthe, uthe@email.unc.edu1. (1) Department of Chemistry, University of North Carolina at Chapel Hill, 238 Caudill Laboratories, Chapel Hill, NC 27599, (2) Curriculum in Applied and Materials Sciences, University of North Carolina at Chapel Hill, Caudill Laboratories, CB# 3290, Chapel Hill, NC 27599
Biomaterials contained in therapeutic or medical devices that are in contact with biological tissue or fluids typically involve to some degree the use of synthetic polymers. While the polymers used for these materials have already helped to make an enormous impact on the healthcare industry, several limitations are left to be addressed. Specifically, materials with tunable solubility, crystallinity, reactivity, and degradability are required. We will discuss our efforts toward developing materials that address these limitations: Polyester-based biodegradable elastomers, functional cyclic monomer-based polyesters, polyurethane elastomers, and amine functionalized gene delivery vectors. A structure-property approach toward the synthesis of these materials will be described.
 

Functional Nanomaterials from New Polymer Synthetic Methodologies
2:00 PM-5:50 PM, Monday, April 7, 2008 Hilton New Orleans Riverside -- Grand Salon 7/10, Oral

Division of Polymer Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008