PHYS 389 |
| DNA bases are the only nucleic acid components that can be electronically excited by solar UV irradiation. The deactivation of excited bases produces reactive oxygen species including singlet oxygen which may be cytotoxic to the cells. Typical singlet oxygen kinetic decay was observed from DNA base photosensitization at 266 and 355 nm with the aids of a nanosecond Nd:YAG laser and a liquid nitrogen cooled Ge detector. The quantum yields of singlet oxygen production were measured to be in the range between 0.08-0.13 for adenine, cytosine and thymine in methanol. The ribose ring attached to the bases does not show any effect on singlet oxygen formation. |
|
PHYS Poster Session - General Experiment
7:30 PM-10:00 PM, Wednesday, April 9, 2008 Morial Convention Center -- Hall A, Poster
Sci-Mix
Division of Physical Chemistry |