Etiology of a research-supportive undergraduate curriculum in forensic science

CHED 1615

Michael H. Silveira, msilveir@ololcollege.edu1, Raymond L. McDaniels1, Aisha I. Paul1, and Frank R. Fronczek, ffroncz@lsu.edu2. (1) Forensic Science Program, Department of Sciences, Our Lady of the Lake College, 5345 Brittany Drive, Baton Rouge, LA 70808, (2) Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803-1804
Diphenyl ethers are structural elements found in medicinally useful antibiotics such as vancomycin as well as in biological toxins in the environment such as dioxins. The purpose of this paper is to report the characterization of a trisubstituted derivative of diphenyl ether via spectral analysis. The structure elucidation of a previously unreported sodium salt of the 2'-sulfonic acid derivative of 4-methyl-4'-nitrodiphenyl ether has been accomplished by IR, 1H NMR, 13C NMR, X-ray, and elemental analysis. An X-ray analysis has shown the stoichiometry to be Na [C13H10N05S]. 3.5(H2O). The structure is polymeric, with Na+ ions (purple) bridged by either 3 water molecules (around a twofold axis) or 2 water molecules (about an inversion center). One of the water molecules is not coordinated to Na, but forms hydrogen bonds. The precision of the X-ray determination was high. The multi-step synthesis of the highly functionalized compound was designed by retro-synthetic analysis.
 

General Papers
1:00 PM-3:40 PM, Thursday, April 10, 2008 Hilton New Orleans Riverside -- HEC A, Oral

Sci-Mix
8:00 PM-10:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Sci-Mix

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008