POLY 277 |
| Organocatalytic ring-opening polymerization (ROP) initiated from a macroinitiator, poly(ethylene glycol) (PEG) enables amphiphilic block copolymers with different functionalities by employing cyclic carbonates derived from 2,2-bis(methylol)propionic acid (bis-MPA) on the ROP monomers for the construction of hydrophobic blocks. The copolymerization of two carbonate monomers based on bis-MPA allows uniform distribution of functional groups in the hydrophobic block, while copolymerizations with the typical cyclic carbonate monomer, trimethylene carbonate (TMC) induce gradient copolymers. These functionalized polycarbonate-PEG block copolymers promise a wide range of applications to biomedical devices due to the biodegradability of aliphatic polycarbonate backbone and the biocompatibility of bis-MPA. |
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Functional Nanomaterials from New Polymer Synthetic Methodologies
2:00 PM-5:50 PM, Monday, April 7, 2008 Hilton New Orleans Riverside -- Grand Salon 7/10, Oral
Division of Polymer Chemistry |