Microfluidic approaches for biochemical detection sensors

COLL 500

Kyung Choi, Chemistry, University of California, Irvine, CA 92697
In nanotechnology, there are a lot of efforts for developing smaller and more compact devices to meet our growing demands in miniaturization. New advances such as soft lithography and microfluidic approaches thus have gotten great attentions to fabricate smaller devices with enhanced performances. There are challenges in nanotechnology for chemists to develop new materials since the technology is a part of the chemical domain, which builds up novel materials at the molecular level. Microfluidic approaches have taken intensive attractions since microfluidic reactors allow us to produce novel materials with specific advantages. We present here a microfluidic particle synthesis of molecularly imprinted polymer (MIP) with high affinities in molecular recognitions for bio- or chemical detection sensors/device applications. Molecularly imprinted polymer can be provided by “molecular imprinting technique”, which is a general protocol for the creation of synthetic receptor sites with specific molecular recognition functions for organic or bio-molecules in cross-linked network polymers. Synthesis of high affinity receptor sites is a key contribute to achieve high sensitivity in their molecular recognition functions.