Systematic investigation of preparing biocompatible, single, and small ZnS-capped CdSe quantum dots with amphiphilic polymers

COLL 304

Robin E. Anderson, robin.anderson@utoronto.ca, Institute for Biomaterials and Biomedical Engineering, University of Toronto, 164 College St, Toronto, ON M5S 3G9, Canada and Warren C. W. Chan, warren.chan@utoronto.ca, Institute of Biomaterials and Biomedical Engineering, University of Toronto, 4 Taddle Creek Road, Resebrugh Building 407 and 421, Toronto, ON M5S 3G9, Canada.
The successful transfer of nanoparticles between solvents is critical for many applications. We evaluated the impact of amphiphillic polymer composition on the size, transfer efficiency, and biocompatibility of tri-n-octylphosphine oxide-stabilized semiconductor ZnS-capped CdSe and CdS-capped CdTeSe quantum dots (QDs). We also investigated the adsorption of various proteins onto the surface of these QDs and studied the effect of surface chemistry on non-specific protein binding. The results from these studies will have implications in the design of QDs and other nanoparticles for biological and biomedical applications.
 

Polymer-Nanoparticle Systems: Theory, Simulation, Experiments
9:00 AM-12:00 PM, Tuesday, April 8, 2008 Morial Convention Center -- Rm. 227, Oral

Division of Colloid & Surface Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008