Hydrogels based upon random copolymerization of 2-hydroxyethyl acrylate and 2-hydroxyethyl methacrylate: Characterization and controlled drug release

CHED 708

Ashley L. Morris, almorris@stetson.edu and W. Tandy Grubbs, wgrubbs@stetson.edu. Department of Chemistry, Stetson University, Unit 8271, DeLand, FL 32720
Hydrogels have been synthesized by random copolymerization of 2-hydroxyethyl acrylate and 2-hydroxyethyl methacrylate. The degree of water absorption in the swelled hydrogel is found to vary from 80 percent to 600 percent as the monomer fraction of 2-hydroxyethyl acrylate is increased from zero to one. Details of the synthesis and characterization of the hydrogels are presented. Controlled drug release is demonstrated using salicylic acid and acetylsalicyclic acid as a model drug.
 

Undergraduate Research Poster Session: Polymer Chemistry
11:00 AM-1:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster

Division of Chemical Education

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008