PHYS 212 |
| Several groups have demonstrated the promise of using gold materials in the area of cancer therapy. More specifically, the tunable surface plasmons of gold-silica nanoshells in the near-IR region of the spectrum, considered by biologists as the “water window,” can allow for localized heating in a tumor containing nanoshells without damaging surrounding tissue. To allow more efficient delivery of nanoshells in vivo, we are pursuing various surface modification strategies for gold nanomaterials, including the use of bifunctional gold-binding peptides and thiolated folic acid molecules. An overview of nanoshell modification strategies and synthetic techniques will be given along with the use of fluorescence and surface enhanced Raman scattering for the quantification and characterization of various species on the gold-nanoshell surface. The application of these modification techniques to cancer therapy will also be discussed. |
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Spectroscopy, Chemistry, and Imaging through Nanophotonics
8:00 AM-12:00 PM, Tuesday, April 8, 2008 Morial Convention Center -- Rm. 345, Oral
Division of Physical Chemistry |