CHED 819 |
| Nucleosomes, which organize and compact DNA, bind primarily to the sugar-phosphate backbone of sequences, suggesting that the positions at which they bind are random. However, it is known that nucleosomes bind some sequences more strongly than others. Different sets of nucleosome-binding sequences [Kubista, M., et. al. (1997) J. Mol. Biol. 267, 807-817] [Widom, J., et. al. (1998) J. Mol. Biol. 276, 19-42] were analyzed using autocorrelation and cross-correlation positional functions. Certain dimers are prominent and have periodicity in certain sequences. It is the position and deformability of such dimers that stabilize the nucleosome complex. |
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Undergraduate Research Poster Session: Biochemistry
2:00 PM-4:00 PM, Monday, April 7, 2008 Morial Convention Center -- Hall A, Poster
Division of Chemical Education |