TOXIMonday, August 20, 2007

8:00 PM-10:00 PM BCEC -- Exhibit Hall - B2, Sci-Mix
Sci-Mix
Organizer:Kent S. Gates
 A rule-based method for comprehensive risk assessment of the mutagenic potential of drugs
Catrin Hasselgren Arnby, Lars Carlsson, Claire Gavaghan, Scott Boyer
 A survey of RNA damage products in the SJL mouse model of inflammation
Bo Pang, Jose L. McFaline, Matthew R. Sullivan, C. Eric Elmquist, Peter C. Dedon
 Aldo-keto reductase 1C3 regulates prostaglandin signaling in breast cancer
Michael C. Byrns, Seon Hwa Lee, Ling Duan, Ian A. Blair, Trevor M. Penning
 Chemical properties of malondialdehyde nucleoside adducts and their amino acid crosslinks
Joseph Szekely, Carmelo J. Rizzo, Lawrence J. Marnett
 Defining the spectrum of protein carbonyls formed in cytochrome C by peroxidation of linoleic acid
Junghyun Son, Michelle V. Williams, John S. Wishnok, Steven R. Tannenbaum, Peter C. Dedon
 DNA polymerase V allows bypass of toxic guanine oxidation products in vivo
William L. Neeley, Sarah Delaney, Yuriy O. Alekseyev, Daniel F. Jarosz, James C. Delaney, Graham Walker, John M. Essigmann
 Drug metabolism in 3-D perfused microreactor liver cultures
Ju Liu, Walker Inman, Sharon Karakattu, Michal Bokayza, Karel Domansky, Keith Hoffmaster, Linda G. Griffith, Steve R. Tannenbaum
 Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: Enhanced mobility in TGT explains conformational heterogeneity, more flexible bending and greater nucleotide excision repair susceptibility
Yuqin Cai, Nicholas E. Geacintov, Suse Broyde
 Effect of sequence context on rate and yield of interstrand crosslinks generated by abasic sites in duplex DNA
Derrick R. Seiner, Sanjay Dutta, Kent S. Gates
 Formation of 2′-deoxyguanosine adducts from 12(S)-hydroperoxyeicosatetraenoic acid
Seon Hwa Lee, Clementina Mesaros, Ian A. Blair
 Glutathione concentration and the aerobic fate of the C3'-thymidinyl radical in DNA
Rehana Ali Zaidi, Amanda C. Bryant-Friedrich
 Identification of covalent DNA adducts in vitro from bioactivation of pentachlorophenol
V G Vaidyanathan, Peter W. Villalta, Shana J. Sturla
 Identification of nitrated proteins from iNOS-induced macrophages using biotin labeling and capture
Jennifer R. Seal, John S. Wishnok, Steven R. Tannenbaum
 In vitro replication study of an intrastrand crosslink lesion G[8-5m]T and 8-oxo-2'-deoxyguanosine/thymidine glycol tandem lesion
Yong Jiang, Yinsheng Wang
 Insights into the determinants of the quantity and chemistry of sequence-selective guanine oxidation in DNA
Yelena Margolin, Vladimir Shafirovich, Nicholas E. Geacintov, Peter C. Dedon
 Novel modification of amyloid beta peptides by metal-catalyzed oxidation
Tomoyuki Oe, Koichi Inoue, Clementina Mesaros, Carlos O. Garner, Bradley L. Ackermann, Ian A. Blair
 Planar chirality due to a polysulfur ring in natural pentathiepin cytotoxins. Implications of planar chirality for enantiospecific biosynthesis and toxicity
Adaickapillai Mahendran, Edyta M. Brzostowska, Martine Paulynice, Ronald Bentley, Alexander Greer
 Shoot the messenger: c-Jun-N-terminal kinase (JNK) and nuclear factor-kappaB (NF-κB) pathway components are sensors for reactive electrophiles
Hansen L. Wong, Jeremy S. Myers, Simona G. Codreanu, Christopher R. Orton, Matthew E. Szapacs, Raymond W. Ganster, Dean W. Ballard, Daniel C. Liebler
 Structural characterization of 1,N2-ethenodeoxyguanosine in the dodecamer 5'-CGCATethenoGGAATCC-3'
Ganesh Shanmugam, Ivan D. Kozekov, F. Peter Guengerich, Carmelo J. Rizzo, Michael P. Stone
 Studies on N1-inosine and N6-adenine adducts in mice after inhalation exposures to 1,3-butadiene
Gunnar Boysen, Mitchell Troutman, Leonard B. Collins, James Swenberg
 Synthesis of alpha-methylene-deoxynucleotide triphosphates (alpha-m-dNTP) as non-cleavable substrates for polymerases
Fengting Liang, Nidhi Jain, A. S. Prakasha Gowda, Thomas E. Spratt, Bongsup Cho
 Translesion synthesis past the Me-FAPy adduct in oligonucleotides by DNA polymerases
Plamen P. Christov, Ivan D. Kozekov, Kyle L. Brown, Michael P. Stone, Thomas M. Harris, Carmelo J. Rizzo

Symposium Grid -- Division of Chemical Toxicology -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007