Session: Protein-Nucleic Acid Interactions: Experimental and Modeling Analysis


COMP		Monday, August 20, 2007

8:30 AM-12:15 PM BCEC -- 156B, Oral
Protein-Nucleic Acid Interactions: Experimental and Modeling Analysis

Organizer:	Mihaela Rita Mihailescu
Presiding:	Tim Evans
8:30 AM	140	Deducing the multiple binding modes of p53 tetramer – DNA interaction based on full-site palindrome of p53 response elements Buyong Ma, Arnold J. Levine
9:00 AM	141	How does a protein find its site on DNA? Leonid Mirny
9:30 AM	142	Fragile X mental retardation syndrome: Structure of the KH1-KH2 domains of fragile X mental retardation protein Lynne Regan, Roberto Valverde, Irina Pozdnyakova, Tommi Kajander, Janani Venkatraman
10:00 AM		Intermission
10:15 AM	143	Mechanism of RNA binding by RNA recognition motifs Kathleen B. Hall
10:45 AM	144	Probing the structure and activity of DNA-/RNA-processing enzymes with the 2,4-difluorotoluyl/ribo-2,4-difluorotoluyl (dF/rF) nucleoside, an apolar thymidine/uridine analog Martin Egli, Pradeep S. Pallan, Feng Li, Adriana Irimia, Robert L. Eoff, Jie Xie, Anne Noronha, Kallanthottathil G. Rajeev, F. Peter Guengerich, Eriks Rozners, Muthiah Manoharan
11:15 AM	145	Design of a protein ring sequencer via SMD simulations of RNA translocation Ioana Cozmuta, Viktor Stolc
11:45 AM	146	On nucleic acid flexibility using continuum solvent models Yannick J. Bomble, David A. Case

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