ORGNThursday, August 23, 2007
8:00 AM-12:00 PM BCEC -- 253B, Oral
Biologically-Related Molecules and Processes
Presiding:M-E. Duban
8:00 AM957Modifications of the N-terminus of polyamides resulted in compounds with enhanced DNA binding sequence specificity
Toni Brown, Hilary Mackay, Mark Turlington, Arden Sutterfield, Traci Smith, Laura Westrate, Alan Sielaff, Chrystal D. Bruce, Jerome Kluza, Caroline O'Hare, Binh Nguyen, John Hartley, David Wilson, Moses Lee
8:20 AM958Toward the development of light-regulated antisense methodologies
Hrvoje Lusic, Alexander Deiters
8:40 AM959Development of photochemical tools for gene regulation
Douglas D. Young, Alexander Deiters
9:00 AM960Amphiphilic polymers endowed with desirable antimicrobial properties
Gregory J. Gabriel, Jeffrey M. Dabkowski, Gregory N. Tew
9:20 AM961Discovery aimed at Gram-positive antibacterials, 1. Mannich base mechanism-based inactivation of sortase via an apparent E1cb elimination
M-E. Duban, Anthony W. Maresso, Ruiying Wu, Justin W. Kern, Rongguang Zhang, Dorota Janik, Dominique M. Missiakas, Andrzej Joachimiak, Olaf Schneewind
9:40 AM962Anomeric Pudovik rearrangement
Kehinde Ajayi, Spencer Knapp
10:00 AM963Design and synthesis of nucleoside analogs to probe RNA-editing mechanism
Olena Maydanovych, Peter A Beal
10:20 AM964Enzymatically cleavable fluorescent nucleotides for DNA sequencing by synthesis: Design, synthesis and proof of concept
Maria Lopalco, Jin Ku Cho, Mark Bradley
10:40 AM965Lethal mutagenesis of RNA viruses: Design of artificial nucleosides as antiviral agents
Jocelyn P. Edathil, Craig E. Cameron, Blake R. Peterson
11:00 AM966Mimicry of exposed phosphocholine on damaged cells: Synthetic cell surface receptors that bind C-reactive protein promote apoptosis of lymphocytes
Qi Sun, Sonalee Athavankar, Blake R. Peterson
11:20 AM967Photolabile reporters of molecular recognition: Caging, tagging and photoamplification
Andrei G. Kutateladze, Tiffany P. Gustafson, Roman A. Valiulin
11:40 AM968Novel blockers of the M2 channel of influenza virus, 1 Inhibitor design, and first active agents
M-E. Duban, Steven P. Lee, Dorota Janik, Chunlong Ma, Victoria Balannik, Dale J. Kempf, Lawrence H. Pinto

Previous Session -- Biologically-Related Molecules and Processes

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007