BIOTWednesday, August 22, 2007

5:30 PM-7:30 PM BCEC -- Exhibit Hall - B2, Poster
Poster Session
Upstream Processing
Organizers:Yi Tang
S. Ozturk
Shyamsundar Subramanian
Role of astroglial fatty acid metabolism in the pathogenesis of Alzheimer's disease: A metabolic flux analysis (MFA) study
Sachin Patil, Christina Chan
Suppression of PKR activity mediates the apoptosis induced by palmitic acid and TNF-α in HepG2 cells
Xuerui Yang, Christina Chan
Studies on novel optimization parameters for production of protease using response surface methodology
Asha Immanuel Raju Chaduvula, Kiran Kumar Nalla, Murali Yugandhar Nikku, Sarat Babu Imandi, Sita Kumari Karanam, Israel Yedluri
Evaluating biopharmaceutical economics and capacity with process modeling and simulation
Alexandros Koulouris, Charles Siletti, Demetri Petrides
Monitoring the expression of biosynthetic pathway genes in Catharanthus roseus hairy root cultures under optimum elicitation conditions
Sheba Goklany, R. H. Loring, Carolyn WT. Lee-Parsons
Analysis of suspended and biofilm atrazine degrading cells
Nicole Kim Biglione, Victor GJ. Rodgers, Tonya L. Peeples
Biosynthesis and application of colorants from fungi
Farzaneh Alihosseini, Gang Sun
The evolution of a disposable stirred tank bioreactor at Centocor: From concept to GMP implementation
Wood Christian, Ravinder Bhatia, Nicole Richardson, Sadettin Ozturk
Biotransformation of steroids by Exophiala jeanselmei var. lecanii corni
Kayanne Patrice McCook, Paul B. Reese
Multiplex transcript analysis for identifying high-producing cell lines
Christina J Lee, Gargi Seth, Joni Tsukuda, Robert W Hamilton
ReBiT, a database for enzymatic pathway design
Collin H. Martin, Darcy Prather, Kristala Jones Prather
Construction of ptb disrupted mutant for characterization of its function in Clostridium tyrobutyricum fermentation
Yali Zhang, Shang-Tian Yang
Biotransformation of steroids by Thielaviopsis paradoxa
Floyd Alexander Russell, Paul B. Reese
Continuous perfusion process in a disposable stirred-tank bioreactor: A case study
Barbara Chiang, Nicole Richardson, Hong Haddock, Christian Wood, Ravinder Bhatia, Sadettin Ozturk
Screening of strains for bioconversion from DL-ATC to L-cysteine
Tao Dong, Zhao Lin, Yu Huang
Development of generic feed media for protein production in contract manufacturing
Guangli Wang
Enhancement of mass transfer in a 250 L bioreactor by sparger design modification
Christian Wood, Hong Haddock, Brian Cottee, Sadettin Ozturk
Fed-batch process development: A platform-based approach
Kristin Stoeber, Colette Ranucci, Natalie Villani
Fluid mixing practice for bioreactor scale-up and scale-down
Richard D. LaRoche
Host system choice challenges bioprocessing of plant-derived therapeutics
Lisa R. Wilken, Susan Woodard, Georgia Barros, Steve White, Zivko L. Nikolov
Implementing an automated reactor sampling system for monitoring cell culture bioreactors
Lauren Speciner, George Barringer, Joseph Perez, Chris Grimaldi, Richard Reineke, Adema Arroyo
Physiological characterization of Saccharopolyspora erythraea deletion strains: Global and pathway specific regulators
Isaac Adedeji Akinrinsola
Production of Galacto-oligosaccharides from whey lactose by using two-step Plug-Flow Reactor with immobilized enzyme β-Galactosidase from Aspergillus oryzae and Bacillus circulans and posterior chromatographic separation
Juan Ignacio Sanz Valero, Shang-Tian Yang
Rapid enhancement of antibody production through DOE-based hydrolysate supplementation of an optimized base medium
Cindy Hunt, Kimesha Hammett, Tammy Hill, Toyin Oshunwusi, Stacy Holdread, Yunling Bai, James W. Brooks
Simultaneous determination of multiple components in CHO cell culture using raman spectroscopy
Samir Varma, Sivakesava Sakhamuri, Michael Hausladen, Zhengjian Li, Steven S. Lee
Strategies for implementation of a new bioprocess container in commercial biologics manufacturing
Rachael Marcklinger, Carolyn Williamson, Joel Gates, Abhinav A Shukla, Steven Lee
Toward reproducible and optimal operation of mammalian cell cultures: A model based approach for fault detection and isolation
Srinivas Karra, M. Nazmul Karim
Using CFD to model gas transfer in bioreactors
William J. Kelly, Joseph Anderson
Improvement of the bleachability and brightness of wheat straw chemomechanical pulp with a pretreatment of xylanase from Trichoderma reesei
Feng Hong
Using MAb enhancing compounds to investigate the MAb production pathway
Tiffany D. Rau, R. Robert Balcarcel
Analysis of gene dosage effects for metabolic engineering in Escherichia coli
Neidi Negron Rodriguez, Kathryn Schumacher, Kristala Jones Prather
Analysis of substrate metabolism for an immobilized CYP2C9 construct: A potential bioreactor application
Lance Wollenberg, Jarod L. Kabulski, Timothy S. Tracy, David Lederman, Peter M. Gannett
Isolation and identification of acetic acid bacteria from Shanxi superior mature vinegar in China
Ning Yang, Lin Hao
Effect of β-Mercaptoethanol on the fed-batch performance of GS-NS0 cells
Zubia Naji, Serena Fries, Michel Chartrain, Craig Seamans
Engineering of an L-arabinose metabolic pathway in Corynebacterium glutamicum
Miho Sasaki, Hideo Kawaguchi, Shohei Okino, Toru Jyojima, Masayuki Inui, Hideaki Yukawa
Novel large-scale production of genetically engineered elastin-like-biopolymer and endotoxin-binding peptide fusion for neutralization of endotoxin
Wenzhao Jia, Yu Lei
Establishment of a WaveTM bioreactor scale-down model for process development and characterization studies
Sarwat F. Khattak, Sivakesava Sakhamuri, Zhengjian Li, Steven Lee
Expression of recombinant human erythropoietin having more complex N-glycans in Drosophila S2 cells through hexosaminidase inhibition
Yeon Kyu Kim, Kyoung Ro Kim, Young Hwan Kim, Hyung Joon Cha
Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures
Nilou Arden, Brian S. Majors, Shin-hyung Ahn, George A. Oyler, Michael J. Betenbaugh
Monitoring of glucose in cell culture by glucose binding protein (GBP) combined with ultraslow microdialysis
Xudong Ge, Michael A. Hanson, Govind Rao, Leah Tolosa
The impact of residual air in bioreactor sterilization
William J. Kelly, Stephen Hannon, Monica Paddock, T. Bruce Vickroy
Optimization of monoclonal antibody production using process simulation and scheduling tools
Victor Papavasileiou, Demetri Petrides, Charles Siletti
Proteomic investigation of elicited Eschscholzia californica cultures producing enhanced levels of benzophenanthridine alkaloids
John T. Oldham, Marina Hincapie, Tomas Rejtar, Jennifer G. Dy, Carolyn WT. Lee-Parsons
Rational design of main-chain elongated substrates acceptable by the E.coli ribosome
Keigo Mizusawa, Shinsuke Sando, Yasuhiro Aoyama
Using a global model of protein production with substrate competition to explain the complex mRNA vs. protein relationship arising from genetic perturbations
Robert S. Kuczenski, Kelvin H. Lee
Recombinant baculovirus-based multiple protein expression platform for Drosophila S2 cell culture
Kyoung Ro Kim, Yeon Kyu Kim, Hyung Joon Cha
Systematic approach to troubleshooting in support of a late stage antibody manufacturing campaign
Le Ly, Michelle Wyckoff, Ching Lee, Valerie Tsang, Helena Yusuf-Makagiansar
Reduction in high mannose glycoforms in mammalian cell culture through media optimization
Nicole Le, Bob Pendleton
Development of novel sourdoughs with the use of different cereal flours
Humberto Hernandez-Sanchez, Ixchel Nava-Arenas
Production of 14-oxo-cis-11-eicosenoic acid from lesquerolic acid by genetically variable Sphingobacterium multivorum strains
Tsung Min Kuo, Alejandro Rooney, Terry A. Isbell
Production of D-lactic acid by the RITE bioprocess using genetically engineered Corynebacterium glutamicum
Shohei Okino, Masako Suda, Masayuki Inui, Hideaki Yukawa, Yoshiki Tsuchida
Effects of redox buffers on the folding of disulfide containing proteins
Watson J. Lees, Minakshi Gurbhele, Farhana Kibria
Paper Withdrawn
A simple and generic immunoplatform for detecting histidine tagged proteins based on biofabrication
Hsuan-Chen Wu, Xiaowen Shi, Angela T. Lewandowski, Chen-Yu Tsao, Rohan Fernandes, Chi-Wei Hung, Philip DeShong, Eiry Kobatake, Gregory F. Payne, William E. Bentley

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The 234th ACS National Meeting, Boston, MA, August 19-23, 2007