Session: Upstream Processing: Advances in Cell Culture Process Development


BIOT		Wednesday, August 22, 2007

8:00 AM-10:30 AM BCEC -- 107C, Oral
Upstream Processing: Advances in Cell Culture Process Development

Organizers:	Susan T. Sharfstein Ilse Blumentals Gargi Maheshwari
8:00 AM		Introductory Remarks
8:05 AM	200	High-producing CHO-GS and NS0-GS cell line generation and characterization using Cell Xpress(TM) technology Nan Lin, Genova Richardson, Lynn Davis, Kimberly Lacy, Misa Gray, Jennifer Cresswell, Anne Dennett, Mark Gerber, Matthew Caple, Kevin Kayser
8:25 AM	201	Developments in using the ACE System to generate high MAb expressing, stable CHO cell lines Malcolm L. Kennard
8:45 AM	202	Proteomic and genomic studies of mammalian cell physiology to optimize production of therapeutic and diagnostic proteins Duan Shen, Thomas R. Kiehl, Susan T. Sharfstein
9:05 AM		Intermission
9:25 AM	203	Impact of scale and bioreactor type on cell growth, productivity, product quality, and global gene expression Michael A. Hanson, Jose Vallejos, Xudong Ge, Kurt Brorson, Antonio R. Moreira, Govind Rao
9:45 AM	204	Sodium butyrate stimulates mAb over-expression in CHO cells by improving gene accessibility Zhou Jiang, Susan T. Sharfstein
10:05 AM	205	Improved analytical technique for high throughput analysis of glycoforms Michael P. Gillmeister, Noboru Tomiya, Scott J. Jacobia, Yuan C. Lee, Stephen F. Gorfien, Michael J. Betenbaugh
10:25 AM		Concluding Remarks

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