COMPTuesday, August 21, 2007

1:00 PM-4:15 PM BCEC -- 161, Oral
Drug Discovery
Virtual Screening
Organizer:Irache Visiers
Presiding:Diane Joseph-McCarthy
1:00 PMFITTED 2.0: A program for flexible protein-flexible ligand docking
Nicolas Moitessier, Christopher R. Corbeil, Pablo Englebienne
1:20 PMDOVIS: A high performance computing tool for virtual screening using AutoDock
Xiaohui Jiang, Kamal Kumar, Anders Wallqvist, Jaques Reifman
1:40 PMFinding the best protocol for enzyme activity modeling
Scott A. Wildman, Robert V. Stanton
2:00 PMCan we improve the structure-based virtual screen hit rate by proposing limited number of VS hits?
Suo-Bao Rong, John van Drie
2:20 PMIdentification of weak leads with virtual screening
Natasja Brooijmans, Christine Humblet
2:40 PMIntermission
2:55 PMSurflex-dock: Effects of protomol generation and fragment matching on docking results
Essam Metwally, Jennifer K Shepphird
3:15 PMThe Shiraz Challenge: The unlovable in search of the undruggable
Kim Branson, Gregory L. Warren
3:35 PMTrixX-BMI: Fast virtual screening using compressed Bitmap Index Technology for efficient prefiltering of Compound Libraries
Jochen Schlosser, Matthias Rarey
3:55 PMUnderstanding false positives in reporter gene assays: In silico chemogenomics approaches to prioritize cell-based HTS data
Meir Glick

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The 234th ACS National Meeting, Boston, MA, August 19-23, 2007