COMPTuesday, August 21, 2007

6:00 PM-8:00 PM BCEC -- Ballroom Foyer, Poster
Poster Session
Organizer:Jeffry D. Madura
Many body interactions of small water clusters
Albert A. DeFusco III, Jun Cui, Kenneth D. Jordan
Molecular dynamic simulations of peptide nucleic acids modified with cycloalkanes
Anna K. Manukyan, Jennifer L. Poutsma
A microfludic device to study ice crystal growth and interactions of antifreeze proteins with ice crystals
Yeliz Celik, Natalya Pertaya, JS. Wettlaufer, Peter L. Davies, Ido Braslavsky
A novel use for protomols in Surflex-Dock: Searching for binding sites with a global protomol
Essam Metwally, John Begemann
Accurate sampling using stochastic dynamics
Giovanni Bussi, Michele Parrinello
New methods for efficient direct calculation of drug binding free energies
Michael R. Shirts, John D. Chodera, Richard A. Friesner
Analysis of protonic and deuteronic basis functions using Gaussian-type functions
Takayoshi Ishimoto, Masanori Tachikawa, Yuichi Inadomi, Hiroaki Umeda, Toshio Watanabe, Umpei Nagashima
Analysis of solvent-solute interactions and its effect on crystal morphology
Charles Acquah, Arunprakash T Karunanithi, Luke EK Achenie, Jose A. Gascon, Shanthakumar Sithambaram, Steven L Suib
Antiviral drug design: Cross-docking to influenza neuraminidase
Jeremiah E Shipman, Robert C. Rizzo
Are enzyme active sites built in multiple layers?
Heather Brodkin, Mary Jo Ondrechen, Dagmar Ringe
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong Hyun Jung, Seung-Hoon Choi, Sang-Kee Kang, Min-Kook Kim, Yun-Jaie Choi
Brownian dynamics simulations of glycolytic enzymes interacting with tubulin
Eric Njankwa Njabon, Neville Y. Forlemu, Kathryn A. Thomasson
Charge-ELF: Addressing conformational dependency of small-molecule atomic charges for biomolecular simulations
Daniel J. McKay, Christopher I. Bayly
Comparative analysis of the molecular recognition within ATP binding pockets of GHKL-family proteins
Minghu Song, Weiwen Ying, Lijun Sun
Computational analysis of the peptide bond formation mechanism in peptidyl transferase
Wenlong A. Tian, Philip M. Kiefer, Roberto Bianco, James T. Hynes
Computational analysis of the search and recognition mechanism of the formamido-pyrimidine DNA glycosylase
Kun Song, Carlos De los Santos, Arthur P. Grollman, Carlos L. Simmerling
Computational binding models for ligands with EGFR: Characterizing the basis of resistance
Trent E. Balius, Robert C. Rizzo
Computational characterization of amyloidogenic mutations in protein sequences
Jiwon Choi, Hui Sun Lee, Ma Qinqin, Sukjoon Yoon
Computational modeling of a crystal structure
Marija L Mihajlovic, Petar M Mitrasinovic
Computational study of Bacillus anthracis glutamate racE2
Wentao Fu, Shahila Mehboob, Michael E. Johnson
Computational study of interaction between argadin and acidic mammalian chitinase
Hiroaki Gouda, Shuichi Hirono
Computer-aided design of vancomycin analogs for efficient binding of both D-Ala-D-Ala and D-Ala-D-Lac
Siegfried S. F. Leung, Julian Tirado-Rives, William L. Jorgensen
Correction of charge-transfer indices for multifunctional amino acids
Francisco Torrens, Gloria Castellano
Design of quantum sieves for seperation of hydrogen isotopes
Yaobao Ping
Docking studies of cytochrome P450-2D6 inhibitors
Ray J Unwalla, Jason Cross, Sumeet Salaniwal, John Kao, Adam Shilling, Louis Leung
Downfolding and N-ization of a localized AO or LCAO basis set
Eva D. Zurek, Jochen Autschbach, Ole Krogh Andersen
Efficient parallel Fock matrix construction on the Grid
Hiroaki Umeda, Yuichi Inadomi, Toshio Watanabe, Takayoshi Ishimoto, Umpei Nagashima
Enhancing sampling and relating kinectics rates from all-atom explicit solvent accelerated molecular dynamics simulations
Cesar Augusto F. de Oliveira, Donald Hamelberg, J Andrew McCammon
Evaluation of pharmacophore modeling based virtual screening: comparative assessment of catalyst, phase and MOE at the example of HRV coat protein
Martina Mangold, Gudrun Maria Spitzer, Theodora M. Steindl, Hannes G. Wallnoefer, Christian Laggner, Thierry Langer, Klaus Roman Liedl
Examining the role of conformational changes in HIV protease drug resistance
Melinda M. Layten, Fangyu Ding, Carlos L. Simmerling
Experimental and molecular docking simulation studies of Histone deacetylases (HDACs) enzyme inhibitors
Kemal Yelekci, Gamze Bora, Didem Dayangac-Erden, Peruze Ayhan, Sevim Dalkara, Ayhan S. Demir, Hayat Erdem-Yurter
Exploration of the sequence dependent stability of helical content using short alanine peptides
Fangyu Ding
How to improve structure-based pharmacophores by modeling the binding site shape
Sabine Grona, Patrick Markt, Johannes Kirchmair, Daniela Schuster, Thierry Langer, Christian Laggner
Identification of non-peptidic cell recognition motifs applying hybrid structural based computational methods: Development of an in vitro validation assay
Ronald J. Perez
Improved multistate empirical valence bond model for aqueous proton transport
Hanning Chen, Yujie Wu, Feng Wang, Pu Liu, Gregory A. Voth
Inactivation mechanism of [FeFe]-Hydrogenase H-cluster by oxygen
Daniela Dogaru, Stefan Motiu, Valentin Gogonea
Interaction analysis between EGF receptor and EGF by fragment molecular orbital calculation
Toshio Watanabe, Takayoshi Ishimoto, Yutaka Tamura, Yuichi Inadomi, Hiroaki Umeda, Umpei Nagashima
Interactions of antifreeze proteins with ice crystals and cell membranes
Özge Can, Suresh Essampally, Nolan B. Holland
Investigation of MDM2-inhibitor interactions by molecular dynamics and free energy calculations
Yipin Lu, Dongguang Qin, Chao-Yie Yang, Ke Ding, Zaneta Nikolovska-Coleska, Shaomeng Wang
Modeling the flexibility of alpha helices in protein interfaces: Structure based design and prediction of helix mediated protein-protein interactions
James R. Apgar, Xiaoran F. Stowell, Karl N. Gutwin, Amy E. Keating
Molecular dynamics simulations of bound VEGF
Bruno A. C. Horta, Ricardo Bicca Alencastro
Molecular mechanics force fields for modeling small, drug-like molecules compared to wave function, density functional, and semi-empirical molecular orbital theories
Brian White, Elizabeth A. Amin, Carston R. Wagner, Donald G. Truhlar
Nature of stacking interactions between imidazoacridone intercalators and DNA Base Pairs
Iwona E Weidlich, Sergey G. Tarasov, Christopher J. Michejda, Marc C Nicklaus
New insight into the design of effective Bcl-xl inhibitors
William J. Novak, Goran Krilov
New scoring functions for discovery of lead peptides reversible inhibitors of thrombin
Cristina C. Clement, Manfred Philipp, Julian Gingold
Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques
Jerry Osagie Ebalunode, Zheng Ouyang, Jie Liang, Weifan Zheng
Pharmacophore-based virtual screening: How to obtain the best enrichment rates
Johannes Kirchmair, Stojanka Ristic, Kathrin Eder, Patrick Markt, Gerhard Wolber, Theodora M. Steindl, Christian Laggner, Thierry Langer
Prediction of blood-air and tissue-air partition coefficients: Calculated molecular descriptors vs. experimentally determined properties
Denise Mills, Subhash C. Basak, Brian D. Gute
Prediction of pH-dependent aqueous solubility of histone deacetylase (HDAC) inhibitors
Sree M Vadlamudi, Fredrik Bjorkling, Irene Kouskoumvekaki, Niclas Tue Hansen, Svava Ósk Jónsdóttir
Prediction of pKa values for amino acids and peptides
Shuming Zhang, Jon Baker, Peter Pulay
QSAR approach to modeling membrane permeability
Brian D. Gute, Jim Riviere, Ronald E. Baynes, Subhash C. Basak
Quantum effective potentials: An efficient strategy for quantum dynamics
David Z. Goodson
Quantum mechanics/molecular mechanics study of the catalytic mechanism of Trypanosoma cruzi trans-sialidase
Özlem Demir, Adrian Roitberg
Structure-based virtual screening against SARS-3CLpro: Identification of hits and insights into the process of lead development
Prasenjit Mukherjee, Prashant V. Desai, Larry Ross, Lucile White, Mitchell A. Avery
Structure-LD50 correlations: DFT study on substituted 3-carboethoxy-4-aminoquinolines
Tania C Cordova de Sintjago, Luz Escalante, James Posada, Morella Rodriguez, Gustavo Cabrera
Support vector machines and THEMATICS for precise prediction of interaction sites in proteins from 3-D structure
Wenxu Tong, Mary Jo Ondrechen, Ronald J. Williams
Tautomer generation. pKa based dominance conditions for generating the dominant tautomers
Jozsef Szegezdi, Ferenc Csizmadia
The foundation of the approach of Active Thermochemical Tables: The analysis and manipulation of the Thermochemical Network Graph
Abel Fernandez, Branko Ruscic
Theoretical studies on pillared covalent organic frameworks for the hydrogen storage material
Daejin Kim, Dong Hyun Jung, Seung-Hoon Choi, Sang Beom Choi, Jihye Yoon, Young Ho Jhon, Jaheon Kim
Thermal rearrangement of 2-acetoxy-2,6,6 trimethylbicyclo[3.1.0]hexane: Theoretical elucidation of the mechanism
Kemal Yelekci, Safiye Sag Erdem
Novel fast adaptive algorithm for 3D-shape analysis of protein (HIV protease)-ligand interactions
Vivek K Jalahalli, Sunil Kumar, Xiaoyu Zhang, Rajni Garg
Understanding the binding mechanism of a new class of PTEN inhibitors
Qin Wang, Madhusoodanan Mottamal, Goran Krilov
A classical/quantum chemical approach for quantitative structure activity of flavonoids
Ihsan A Shehadi, Deema K Al Jayousi, Ahmed Al Mehdi
Ab initio molecular dynamics of visual pigment chromophore models
Igor Schapiro, Oliver Weingart, Volker Buss
Benchmarking a variety of QM methods in the calculation of relative conformational and pair-wise energies: Just how reliable are the ″shortcut methods″? A close look at LMP2, RI-MP2 and other correlated methods
Karen A. Rossi, Daniel L. Cheney
Brownian dynamics simulations of lactate dehydrogenase isoforms with actin
Eric Njankwa Njabon, Kristine L. Carlson, Kathryn A. Thomasson
Comparison of semi-empirical quantum mechanics methods applied to biological molecules: Potential and free energy surfaces of alanine and glycine Dipeptides in vacuum and in water
Gustavo de M. Seabra, Ross C Walker, Adrian E Roitberg
Data mining the drug database: Is there such a thing as drug-like space?
Chihae Yang, Guangyu Sun, David Bower, James F. Rathman
Density Functional Theory studies of the interaction of sulfur oxides with large water clusters
Jean M. Standard, Ryan D. Quinn, Mary T. Van der Hoven
Evaluation of docking performance: Comparison of Surflex-Dock with five docking algorithms using the Johnson & Johnson data set
Tamsin E. Mansley, Jennifer K Shepphird, Lei Wang
Investigate the fluorescence quenching and recovering process of beta-cyclodextrin anchored quantum dots
Ming Ning, Richard. E Brown
Investigating the predominant factors which drive receptor-ligand binding for inhibitors selective for MMP-13
Noel A. Carrascal, Robert C. Rizzo
Investigation of the inhibitory pathways of [FeFe]-hydrogenase by means of Quantum Mechanics/Molecular Mechanics
Stefan Motiu, Daniela Dogaru, Valentin Gogonea
Molecular dynamics simulations of a DNA-biosensor
Nolwenn Le Bouch, Josée Brisson, Mario Leclerc
Molecular dynamics studies of zeolites functionalized with transition metal ions
Eugenio Jaramillo, Elia C. Garcia, Raymundo Guzman
Molecular mechanisms of gas surface interactions in hypersonic flow
Ioana Cozmuta
Predicting absolute binding free energies in a model binding site
David L. Mobley, Alan P. Graves, John D. Chodera, Andrea McReynolds, Brian K Shoichet, Ken A. Dill
Prediction of the adsorption orientation of Human Serum Albumin on hydrophobic surfaces using theoretical thermodynamic analysis
Hao-Jen Hsu, Sheh-Yi Sheu, Ruey-Yug Tsay
QSAR modeling of blood–brain barrier permeability of diverse organic compounds
Liying Zhang, Hao Zhu, Tudor I. Oprea, Alexander Tropsha
Topomer CoMFA: Investigation of scope
Gunther Stahl, Richard D. Cramer, Bernd Wendt
Structure-based design of a novel class of beta-secretase (BACE) inhibitors
Charles H. Reynolds, Brett A. Tounge, Allen B. Reitz, Ellen W. Baxter
Trends in ligand efficiency: Where do they come from?
Charles H. Reynolds, Brett A. Tounge, Scott D. Bembenek
3-D-QSAR Combined theoretical study of 5-HT1A-receptor agonists
Ekaterina Bartashevich, Vladimir Potemkin
Multiway QSPR analysis of the acidity constant of some phenolic compounds utilizing quantum topological molecular similarity descriptors
Bahram Hemmateenejad, Taghi Khayamian, Mahnaz Esteki, Afshan Mohajeri
Quantitative structure-retention relationship for the Kovats retention indices of a large set of terpenes: A combined data splitting-feature selection (CDFS) strategy
Bahram Hemmateenejad, Katayoun Javidnia, Maryam Elyasi

Symposium Grid -- Division of Computers in Chemistry -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007