BIOTThursday, August 23, 2007

8:00 AM-11:00 AM BCEC -- 106, Oral
Commercialization of Biologics: Scale-up & Process Design for Commercial Facilities: Debottlenecking and Facility Fit
Organizers:Robert Kiss
Nigel Titchener-Hooker
8:00 AMBiopharmaceutical portfolio management and capacity planning: A stochastic multiobjective optimization approach
Edmund D. George, Suzanne Farid
8:20 AMGauging the technical, regulatory and financial implications of process changes
Inass Hassan, Mark Bulmer, John More, Suzanne Farid
8:40 AMIndustrial case studies of debottlenecking and future proofing through discrete event simulation
P. A. Sinclair
9:00 AMPrototype software methodology for the rapid evaluation of biomanufacturing process options
Sunil Chhatre, Richard Francis, Kieran O'Donovan, Nigel J. Titchener-Hooker, Anthony R. Newcombe, Eli Keshavarz-Moore
9:20 AMIntermission
9:40 AMFacility fit, when should it happen?
Jean D. Harms, Amos M. Tsai, Anurag S Rathore
10:00 AMFacility fit: Ensuring process performance comparability for commercial antibody processes when transferring to differently designed equipment
Keith L. White, Roderick Garcia, Kathleen Carswell, Eric Ordonez, Anuj Bhartiya, Brandy Jones, Todd Renshaw, Robert Kiss
10:20 AMStrategies for increasing downstream capacity
David H Peers, Meliana Ratna
10:40 AMCan modular construction help to address key bottlenecks in the retrofit projects?
Thorsten Kimmel

Symposium Grid -- Division of Biochemical Technology -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007