| MEDI | Tuesday, August 21, 2007 | ||
1:30 PM-4:50 PM BCEC -- 210A, Oral | |||
General Oral Session | |||
| Organizer: | James R. McCarthy | ||
| 1:30 PM | 231 | KXO1: The first non-ATP competitive Src inhibitor for clinical development in oncology applications-1 David G Hangauer, Irwin Gelman, Lyn Dyster, Allen Barnett, Michael Smolinski, Taher Hegab, Lingqiu Gao | |
| 1:50 PM | 232 | KXO1: The first non-ATP competitive Src inhibitor for clinical development in oncology applications-2 David G Hangauer, Irwin Gelman, Lyn Dyster, Allen Barnett, Michael Smolinski, Taher Hegab, Lingqiu Gao | |
| 2:10 PM | 233 | Discovery and chiral synthesis of potent c-Met (HGFR) aminopyridine inhibitors Pei-Pei Kung | |
| 2:30 PM | 234 | New perspectives on the medicinal chemistry of the somatostatin receptor agonist SOM230 Ian Lewis, Rainer Albert, Janos Pless, Rainer Kneuer, Herbert A. Schmid, Antonio P. Silva, Daniel Hoyer, Gisbert Weckbecker, Christian Bruns | |
| 2:50 PM | 235 | Modulation of peripheral serotonin levels by enzyme inhibitors for the potential treatment of irritable bowel syndrome (IBS) Zhi-Cai Shi, Raj Devasagayaraj, Kunjian Gu, Haihong Jin, S David Kimball, Brett Marinelli, Lakshman Samala, Sheldon Scott, Ashok Tunoori, Ying Wang, Yi Zang, Chengmin Zhang, Terry Stouch, Jim Liu, Dave Powell, Weimei Sun, Melissa Yang, Amr Nouraldeen, Alan Wilson, Xiang-Qing Yu | |
| 3:10 PM | 236 | Substituted-pyridine 2-amino-3,5-dihydro-4H-imidazol-4-ones as highly potent, and selective BACE1 inhibitors Michael S. Malamas, Keith Barnes, Yu Hui, Ping Zhou, Albert J Robichaud, Jonathan Bard, Jim Turner, Yun Hu, Kristi Y. Fan, Rajiv Chopra, Matthew Johnson | |
| 3:30 PM | 237 | 8,8-Disubstituted-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amines as highly potent, selective and orally active BACE1 inhibitors Michael S. Malamas, Keith Barnes, Yu Hui, Jim Erdei, Iwan Gunawan, Nowak Pawel, Albert J Robichaud, Jonathan Bard, Jim Turner, Yun Hu, Eric Wagner, Suzan Aschmies, Kristi Fan, Rajiv Chopra, Matthew Johnson | |
| 3:50 PM | 238 | Synthesis and discovery of tropane derivatives as nociceptin receptor agonists for the management of cough Ginny D Ho, Ana Bercovici, Ahmad Fawzi, Xiomara Fernandez, William Greenlee, Eugenia Y. Kiselgof, Robbie L. McLeod, Fay Ng, April Smith Torhan, Zheng Tan, Deen Tulshian, Shu-Wei Yang, Hongtao Zhang | |
| 4:10 PM | 239 | Benzoxazepinones: The discovery of a novel SARM template Stephen Rafferty, Robert Gampe, Bajin Han, Sab A. Randhawa, Eugene L. Stewart, Christopher M. Yates | |
| 4:30 PM | 240 | Peptide cyclodimerization by the Cu(I)-mediated azide-alkyne cycloaddition reaction Reshma Jagasia, Justin M. Holub, Markus Bollinger, Kent Kirshenbaum, MG. Finn | |
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
The 234th ACS National Meeting, Boston, MA, August 19-23, 2007