| MEDI | Sunday, August 19, 2007 | ||
1:30 PM-4:50 PM BCEC -- 210A, Oral | |||
General Oral Session | |||
| Organizer: | James R. McCarthy | ||
| 1:30 PM | 19 | Transition state analysis of the chemical and enzymatic prenylation reactions Mark D. Distefano, Stepan Lenevich, Christopher J Cramer | |
| 1:50 PM | 20 | MB07811: A liver-selective thyroid receptor agonist prodrug for the treatment of hyperlipidemia Serge H. Boyer, Hongjian Jiang, Jason D. Jacintho, M. Venkat Reddy, Haiqing Li, Wenyu Li, William G. Schulz, Jennifer L. Godwin, Scott J. Hecker, Edward E. Cable, Bruce R. Ito, James Fujitaki, Patricia D. Finn, Bao-Hong Zhang, Jinzhao Hou, Paul D. van Poelje, David Linemeyer, Mark D. Erion | |
| 2:10 PM | 21 | Novel small molecule agonists of the integrin CD11b/CD18 as in vivo chemical biology probes Jack Rosa, M. Amin Arnaout, Vineet Gupta | |
| 2:30 PM | 22 | Discovery of potent and selective leukotriene A4 hydrolase inhibitors Cheryl A. Grice, Frank U. Axe, Scott D. Bembenek, Christopher R. Butler, Fawn Coles, Paul J. Dunford, James P. Edwards, Anne M. Fourie, Lars Karlsson, Kathleen Lundeen, Jason Riley, Brad M. Savall, Kevin Tays, Jianmei Wei, Kacy Williams, Xiaohua Xue | |
| 2:50 PM | 23 | Multivalent muscarinic antagonists for the treatment of overactive bladder (OAB) Adam D. Hughes, Kay H. Chin, Sharath S. Hegde, Craig O. Husfeld, Jeffrey R. Jasper, Yuhua Ji, Kristin E. King, Tae Weon Lee, Li Li, Mathai Mammen, Alexander J. McNamara, Trevor K. Mischki, Glenmar P. Obedencio, Tess Pulido-Rios, Tod Steinfeld, Shelley M. Sweazey, Richard D. Wilson | |
| 3:10 PM | 24 | Discovery of BI 1356: A highly potent and long-acting DPP-IV inhibitor with a xanthine scaffold Frank Himmelsbach, Klaus Dugi, Matthias Eckhardt, Holger Fuchs, Ulrike Graefe-Mody, Brian Guth, Elke Langkopf, Ralf Lotz, Michael Mark, Herbert Nar, Peter Sieger, Moh Tadayyon, Leo Thomas | |
| 3:30 PM | 25 | Optimized synthesis of 2-methylamino-pyridodiazepines, potent and selective inhibitors of Helicobacter pylori MurI Pamela J. Hill, Gregory S. Basarab, Bolin Geng, Lawrence MacPherson, George Mullen, Alexander Satz | |
| 3:50 PM | 26 | Development of hydroxy hydantoins, a novel class of MMP-12 inhibitors, for treatment of COPD Kristina Stenvall, Balint Gabos, Michael Lundkvist, Magnus Munck af Rosenschöld, Matti Lepistö, Igor Shamovsky | |
| 4:10 PM | 27 | Discovery of selective and potent T-type calcium channel antagonists Zhi-Qiang Yang | |
| 4:30 PM | 28 | Synthesis and characterization of dapagliflozin, a potent selective SGLT2 inhibitor for treatment of diabetes William N. Washburn, Wei Meng, Bruce A. Ellsworth, Alexandra Nirschl, Peggy J. McCann, Manorama Patel, Ravindar N. Girotra, Gang Wu, Philip M. Sher, Scott A. Biller, Prashant P. Deshpande, Deborah L. Hagan, Joseph R. Taylor, Mary Obermeier, William G. Humphreys, Ashish Khanna, James G. Robertson, Aiying Wang, Song Ping Han, John R. Wetterau, Evan Janovitz, Oliver Flint, Jean M. Whaley | |
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
The 234th ACS National Meeting, Boston, MA, August 19-23, 2007