MEDIThursday, August 23, 2007

9:00 AM-12:00 PM BCEC -- 210A, Oral
Antiarrhythmic Agents
Organizer:John A. Butera
9:00 AMCurrent therapy and innovative targets for treatment of cardiac arrhythmias
James K. Hennan
9:30 AMClass III antiarrhythmic agents: Delayed cardiac repolarization by selective blockade of IKr, IKs or IKur
Harold Selnick
10:00 AMDesign and synthesis of orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation
B. Wesley Trotter
10:30 AMDiscovery of potent gap-junction modifiers as novel antiarrhythmic agents: From stable hexa-peptides to orally available small molecules
John A. Butera, Bjarne Due Larsen, Edward Kerns, Li Di, James K. Hennan, Robert Swillo, Gwen Morgan, Christine Huselton, Ray J Unwalla, Jørgen Petersen
11:00 AMA1 Adenosine receptor agonists as ventricular rate control agents during atrial fibrillation
Jeff Zablocki, Elfatih Elzein, Rao Kalla, Xiaofen Li, Thao Perry, Tim Marquart, Hugh Genin, Mark Micklatcher, John Shryock, Lin Wu, Yuan Li, Yuzhi Wu, Dewan Zeng, Arvinder Dhalla, Irene Lepist, Brian Stafford, Kwan Leung
11:30 AMDiscovery of nicotinamides and related derivatives as potent and selective NCX reverse mode inhibitors
Akio Kakefuda, Takahiro Kuramochi, Hiroyoshi Yamada, Ippei Sato, Issei Tsukamoto, Taku Taguchi, Shuichi Sakamoto

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007